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[Accessed 26/01/2026]

Comorbidities collected within 6 months before the index date included metabolic syndrome (hypertension and dyslipidemia), cardiovascular disorders (heart failure, myocardial infarction, ischemic stroke, peripheral arterial disease, coronary artery disease, cardiovascular disease [CVD]), and chronic kidney disease

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269,270 Although evidence from clinical trials is mixed, multiple randomized controlled trials have reported reductions in fat mass and body weight in overweight and obese subjects after taking 36 grams of CLA per day over time periods ranging from 12 weeks to two years